The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion

BACKGROUND: Epstein-Barr virus (EBV) infection is a well characterized etiopathogenic factor for a variety of immune-related conditions, including lymphomas, lymphoproliferative disorders and autoimmune diseases. EBV-mediated transformation of resting B cells to proliferating lymphoblastoid cells oc...

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Detalhes bibliográficos
Main Authors: Hernando, Henar, Shannon-Lowe, Claire, Islam, Abul B, Al-Shahrour, Fatima, Rodríguez-Ubreva, Javier, Rodríguez-Cortez, Virginia C, Javierre, Biola M, Mangas, Cristina, Fernández, Agustín F, Parra, Maribel, Delecluse, Henri-Jacques, Esteller, Manel, López-Granados, Eduardo, Fraga, Mario F, López-Bigas, Nuria, Ballestar, Esteban
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663113/
https://ncbi.nlm.nih.gov/pubmed/23320978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-1-r3
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