Epstein–Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation

Epstein–Barr virus (EBV) infects and transforms human primary B cells inducing indefinite proliferation. To investigate the potential participation of chromatin mechanisms during the EBV-mediated transformation of resting B cells we performed an analysis of global changes in histone modifications. W...

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Main Authors: Hernando, Henar, Islam, Abul B. M. M. K., Rodríguez-Ubreva, Javier, Forné, Ignasi, Ciudad, Laura, Imhof, Axel, Shannon-Lowe, Claire, Ballestar, Esteban
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874198/
https://ncbi.nlm.nih.gov/pubmed/24097438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt886
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