Central Melanin-Concentrating Hormone Influences Liver and Adipose Metabolism Via Specific Hypothalamic Nuclei and Efferent Autonomic/JNK1 Pathways

BACKGROUND & AIMS: Specific neuronal circuits modulate autonomic outflow to liver and white adipose tissue. Melanin-concentrating hormone (MCH)-deficient mice are hypophagic, lean, and do not develop hepatosteatosis when fed a high-fat diet. Herein, we sought to investigate the role of MCH, an o...

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Detalhes bibliográficos
Main Authors: Imbernon, Monica, Beiroa, Daniel, Vázquez, María J., Morgan, Donald A., Veyrat–Durebex, Christelle, Porteiro, Begoña, Díaz–Arteaga, Adenis, Senra, Ana, Busquets, Silvia, Velásquez, Douglas A., Al–Massadi, Omar, Varela, Luis, Gándara, Marina, López–Soriano, Francisco–Javier, Gallego, Rosalía, Seoane, Luisa M., Argiles, Josep M., López, Miguel, Davis, Roger J., Sabio, Guadalupe, Rohner–Jeanrenaud, Françoise, Rahmouni, Kamal, Dieguez, Carlos, Nogueiras, Ruben
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663042/
https://ncbi.nlm.nih.gov/pubmed/23142626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.10.051
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