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Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance

OBJECTIVE: Glucagon receptor antagonists and humanized glucagon antibodies are currently studied as promising therapies for obesity and type II diabetes. Among its variety of actions, glucagon reduces food intake, but the molecular mechanisms mediating this effect as well as glucagon resistance are...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Metab
Päätekijät: Quiñones, Mar, Al-Massadi, Omar, Gallego, Rosalía, Fernø, Johan, Diéguez, Carlos, López, Miguel, Nogueiras, Ruben
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731730/
https://ncbi.nlm.nih.gov/pubmed/26909312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.09.014
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