Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance

OBJECTIVE: Glucagon receptor antagonists and humanized glucagon antibodies are currently studied as promising therapies for obesity and type II diabetes. Among its variety of actions, glucagon reduces food intake, but the molecular mechanisms mediating this effect as well as glucagon resistance are...

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Detalles Bibliográficos
Publicado en:Mol Metab
Main Authors: Quiñones, Mar, Al-Massadi, Omar, Gallego, Rosalía, Fernø, Johan, Diéguez, Carlos, López, Miguel, Nogueiras, Ruben
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731730/
https://ncbi.nlm.nih.gov/pubmed/26909312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.09.014
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