Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance

OBJECTIVE: Glucagon receptor antagonists and humanized glucagon antibodies are currently studied as promising therapies for obesity and type II diabetes. Among its variety of actions, glucagon reduces food intake, but the molecular mechanisms mediating this effect as well as glucagon resistance are...

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Опубликовано в: :Mol Metab
Главные авторы: Quiñones, Mar, Al-Massadi, Omar, Gallego, Rosalía, Fernø, Johan, Diéguez, Carlos, López, Miguel, Nogueiras, Ruben
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2015
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731730/
https://ncbi.nlm.nih.gov/pubmed/26909312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.09.014
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