Hypothalamic CaMKKβ mediates glucagon anorectic effect and its diet-induced resistance

OBJECTIVE: Glucagon receptor antagonists and humanized glucagon antibodies are currently studied as promising therapies for obesity and type II diabetes. Among its variety of actions, glucagon reduces food intake, but the molecular mechanisms mediating this effect as well as glucagon resistance are...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Metab
Hauptverfasser: Quiñones, Mar, Al-Massadi, Omar, Gallego, Rosalía, Fernø, Johan, Diéguez, Carlos, López, Miguel, Nogueiras, Ruben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731730/
https://ncbi.nlm.nih.gov/pubmed/26909312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.09.014
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