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Inference of Gene Regulatory Networks with Sparse Structural Equation Models Exploiting Genetic Perturbations

Integrating genetic perturbations with gene expression data not only improves accuracy of regulatory network topology inference, but also enables learning of causal regulatory relations between genes. Although a number of methods have been developed to integrate both types of data, the desiderata of...

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Détails bibliographiques
Auteurs principaux: Cai, Xiaodong, Bazerque, Juan Andrés, Giannakis, Georgios B.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662697/
https://ncbi.nlm.nih.gov/pubmed/23717196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003068
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