Human Papillomavirus (HPV) Upregulates the Cellular Deubiquitinase UCHL1 to Suppress the Keratinocyte's Innate Immune Response

Persistent infection of basal keratinocytes with high-risk human papillomavirus (hrHPV) may cause cancer. Keratinocytes are equipped with different pattern recognition receptors (PRRs) but hrHPV has developed ways to dampen their signals resulting in minimal inflammation and evasion of host immunity...

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Autors principals: Karim, Rezaul, Tummers, Bart, Meyers, Craig, Biryukov, Jennifer L., Alam, Samina, Backendorf, Claude, Jha, Veena, Offringa, Rienk, van Ommen, Gert-Jan B., Melief, Cornelis J. M., Guardavaccaro, Daniele, Boer, Judith M., van der Burg, Sjoerd H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662672/
https://ncbi.nlm.nih.gov/pubmed/23717208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003384
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