Human Papillomavirus (HPV) Upregulates the Cellular Deubiquitinase UCHL1 to Suppress the Keratinocyte's Innate Immune Response

Persistent infection of basal keratinocytes with high-risk human papillomavirus (hrHPV) may cause cancer. Keratinocytes are equipped with different pattern recognition receptors (PRRs) but hrHPV has developed ways to dampen their signals resulting in minimal inflammation and evasion of host immunity...

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Main Authors: Karim, Rezaul, Tummers, Bart, Meyers, Craig, Biryukov, Jennifer L., Alam, Samina, Backendorf, Claude, Jha, Veena, Offringa, Rienk, van Ommen, Gert-Jan B., Melief, Cornelis J. M., Guardavaccaro, Daniele, Boer, Judith M., van der Burg, Sjoerd H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662672/
https://ncbi.nlm.nih.gov/pubmed/23717208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003384
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