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Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca(2+) elevation
Connexin mimetic peptides (CxMPs), such as Gap26 and Gap27, are known as inhibitors of gap junction channels but evidence is accruing that these peptides also inhibit unapposed/non-junctional hemichannels (HCs) residing in the plasma membrane. We used voltage clamp studies to investigate the effect...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662472/ https://ncbi.nlm.nih.gov/pubmed/23095853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-012-0304-2 |
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