Myosin II contributes to cell-scale actin network treadmilling via network disassembly

Crawling locomotion of eukaryotic cells is achieved by a process dependent on the actin cytoskeleton(1): protrusion of the leading edge requires assembly of a network of actin filaments(2), which must be disassembled at the cell rear for sustained motility. Although ADF/cofilin proteins have been sh...

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Main Authors: Wilson, Cyrus A., Tsuchida, Mark A., Allen, Greg M., Barnhart, Erin L., Applegate, Kathryn T., Yam, Patricia T., Ji, Lin, Keren, Kinneret, Danuser, Gaudenz, Theriot, Julie A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662466/
https://ncbi.nlm.nih.gov/pubmed/20485438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08994
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