Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

We have analyzed the spontaneous symmetry breaking and initiation of actin-based motility in keratocytes (fish epithelial cells). In stationary keratocytes, the actin network flow was inwards and radially symmetric. Immediately before motility initiation, the actin network flow increased at the pros...

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Hlavní autoři: Yam, Patricia T., Wilson, Cyrus A., Ji, Lin, Hebert, Benedict, Barnhart, Erin L., Dye, Natalie A., Wiseman, Paul W., Danuser, Gaudenz, Theriot, Julie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064654/
https://ncbi.nlm.nih.gov/pubmed/17893245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706012
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