Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

We have analyzed the spontaneous symmetry breaking and initiation of actin-based motility in keratocytes (fish epithelial cells). In stationary keratocytes, the actin network flow was inwards and radially symmetric. Immediately before motility initiation, the actin network flow increased at the pros...

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Main Authors: Yam, Patricia T., Wilson, Cyrus A., Ji, Lin, Hebert, Benedict, Barnhart, Erin L., Dye, Natalie A., Wiseman, Paul W., Danuser, Gaudenz, Theriot, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2007
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064654/
https://ncbi.nlm.nih.gov/pubmed/17893245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706012
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