Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

We have analyzed the spontaneous symmetry breaking and initiation of actin-based motility in keratocytes (fish epithelial cells). In stationary keratocytes, the actin network flow was inwards and radially symmetric. Immediately before motility initiation, the actin network flow increased at the pros...

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Bibliographische Detailangaben
Hauptverfasser: Yam, Patricia T., Wilson, Cyrus A., Ji, Lin, Hebert, Benedict, Barnhart, Erin L., Dye, Natalie A., Wiseman, Paul W., Danuser, Gaudenz, Theriot, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2007
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064654/
https://ncbi.nlm.nih.gov/pubmed/17893245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706012
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