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Cell-Free Hemoglobin and Its Scavenger Proteins: New Disease Models Leading the Way to Targeted Therapies

Hemoglobin (Hb) has multiple pathophysiologic effects when released into the intravascular space during hemolysis. The extracellular effects of Hb have resulted in novel models of toxicity, which help to explain endothelial dysfunction and cardiovascular complications that accompany genetic hemolyti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schaer, Dominik J., Buehler, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662353/
https://ncbi.nlm.nih.gov/pubmed/23645855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a013433
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