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Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Hemolysis occurs in many hematologic and nonhematologic diseases. Extracellular hemoglobin (Hb) has been found to trigger specific pathophysiologies that are associated with adverse clinical outcomes in patients with hemolysis, such as acute and chronic vascular disease, inflammation, thrombosis, an...

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Detalhes bibliográficos
Main Authors: Schaer, Dominik J., Buehler, Paul W., Alayash, Abdu I., Belcher, John D., Vercellotti, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578950/
https://ncbi.nlm.nih.gov/pubmed/23264591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-451229
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