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Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

Hemolysis occurs in many hematologic and nonhematologic diseases. Extracellular hemoglobin (Hb) has been found to trigger specific pathophysiologies that are associated with adverse clinical outcomes in patients with hemolysis, such as acute and chronic vascular disease, inflammation, thrombosis, an...

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Bibliografiske detaljer
Main Authors: Schaer, Dominik J., Buehler, Paul W., Alayash, Abdu I., Belcher, John D., Vercellotti, Gregory M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578950/
https://ncbi.nlm.nih.gov/pubmed/23264591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-11-451229
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