An Engineered Arginase FC Protein Inhibits Tumor Growth In Vitro and In Vivo

Arginine is a semiessential amino acid required for the growth of melanoma and hepatocellular carcinoma, and the enzymatic removal of arginine by pegylated arginine deiminase (ADI) or arginase is being tested clinically. Here, we report a genetically engineered arginase FC fusion protein exhibiting...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Lihua, Wang, Yan, Chen, Jun, Cheng, Bi, Hu, Jiehua, Zhou, Yuehua, Gao, Xin, Gao, Liucun, Mei, Xifan, Sun, Meiyan, Zhang, Zhuomei, Song, Haifeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662114/
https://ncbi.nlm.nih.gov/pubmed/23737831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/423129
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