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TGF-β Signaling Regulates Pancreatic β-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression

Proliferation of pancreatic β-cells is an important mechanism underlying β-cell mass adaptation to metabolic demands. Increasing β-cell mass by regeneration may ameliorate or correct both type 1 and type 2 diabetes, which both result from inadequate production of insulin by β-cells of the pancreatic...

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Detalhes bibliográficos
Main Authors: Suzuki, Tomoyuki, Dai, Ping, Hatakeyama, Tomoya, Harada, Yoshinori, Tanaka, Hideo, Yoshimura, Norio, Takamatsu, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Society of Histochemistry and Cytochemistry 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661777/
https://ncbi.nlm.nih.gov/pubmed/23720603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.12035
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