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Interaction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27

Connexin 43 (Cx43) functions as a cell growth suppressor. We have demonstrated that Cx43 interacts with heat shock cognate protein 70 (Hsc70) for regulating cell proliferation. Hsc70 interacts with CDK inhibitor p27, which regulates the assembly and subcellular localization of cyclin D1-CDK4-p27 com...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hino, Hitoshi, Dai, Ping, Yoshida, Tatsushi, Hatakeyama, Tomoya, Harada, Yoshinori, Otsuji, Eigo, Okuda, Tsukasa, Takamatsu, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612729/
https://ncbi.nlm.nih.gov/pubmed/26481195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15365
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