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Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease

While it is clear that astrocytes and microglia cluster around dense-core amyloid plaques in Alzheimer disease (AD), whether they are primarily attracted to amyloid deposits or are just reacting to plaque-associated neuritic damage remains elusive. We postulate that astrocytes and microglia may diff...

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Detalhes bibliográficos
Main Authors: Serrano-Pozo, Alberto, Muzikansky, Alona, Gómez-Isla, Teresa, Growdon, John H., Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661683/
https://ncbi.nlm.nih.gov/pubmed/23656989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3182933788
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