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mTORC1 Dependent Regulation of REDD1 Protein Stability

REDD1 is known to be transcriptionally upregulated in hypoxia. During hypoxic stress, REDD1 plays an important role as a mediator of mTORC1 inhibition. REDD1 is also subject to highly dynamic transcriptional regulation in response to a variety of other stress signals. In addition, the REDD1 protein...

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Autors principals: Tan, Chia Yee, Hagen, Thilo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661664/
https://ncbi.nlm.nih.gov/pubmed/23717519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063970
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