Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome

It has been established that Adenosine-5'-triphosphate (ATP) can activate the NLRP3 inflammasome. However, the physiological effect of extracellular ATP on NLRP3 inflammasome activation has not yet been investigated. In the present study, we found that ATP was indeed released during bacterial i...

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Bibliographic Details
Main Authors: Xiang, Yang, Wang, Xuan, Yan, Chao, Gao, Qian, Li, Sheng-An, Liu, Jie, Zhou, Kaifeng, Guo, Xiaolong, Lee, Wenhui, Zhang, Yun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661663/
https://ncbi.nlm.nih.gov/pubmed/23717478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063759
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