The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine

The NLR pyrin domain containing 3 (NLRP3) inflammasome is a major component of the innate immune system, but its mechanism of activation by a wide range of molecules remains largely unknown. Widely used nano-sized inorganic metal oxides such as silica dioxide (nano-SiO(2)) and titanium dioxide (nano...

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Publicado en:Cell Death Dis
Autores principales: Baron, L, Gombault, A, Fanny, M, Villeret, B, Savigny, F, Guillou, N, Panek, C, Le Bert, M, Lagente, V, Rassendren, F, Riteau, N, Couillin, I
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4669808/
https://ncbi.nlm.nih.gov/pubmed/25654762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.576
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