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Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome

It has been established that Adenosine-5'-triphosphate (ATP) can activate the NLRP3 inflammasome. However, the physiological effect of extracellular ATP on NLRP3 inflammasome activation has not yet been investigated. In the present study, we found that ATP was indeed released during bacterial i...

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Detalhes bibliográficos
Main Authors: Xiang, Yang, Wang, Xuan, Yan, Chao, Gao, Qian, Li, Sheng-An, Liu, Jie, Zhou, Kaifeng, Guo, Xiaolong, Lee, Wenhui, Zhang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661663/
https://ncbi.nlm.nih.gov/pubmed/23717478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063759
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