Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

Circulating metabolites associated with insulin sensitivity may represent useful biomarkers, but their causal role in insulin sensitivity and diabetes is less certain. We previously identified novel metabolites correlated with insulin sensitivity measured by the hyperinsulinemic-euglycemic clamp. Th...

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Autores principales: Xie, Weijia, Wood, Andrew R., Lyssenko, Valeriya, Weedon, Michael N., Knowles, Joshua W., Alkayyali, Sami, Assimes, Themistocles L., Quertermous, Thomas, Abbasi, Fahim, Paananen, Jussi, Häring, Hans, Hansen, Torben, Pedersen, Oluf, Smith, Ulf, Laakso, Markku, Dekker, Jacqueline M., Nolan, John J., Groop, Leif, Ferrannini, Ele, Adam, Klaus-Peter, Gall, Walter E., Frayling, Timothy M., Walker, Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661655/
https://ncbi.nlm.nih.gov/pubmed/23378610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0876
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