Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes

Circulating metabolites associated with insulin sensitivity may represent useful biomarkers, but their causal role in insulin sensitivity and diabetes is less certain. We previously identified novel metabolites correlated with insulin sensitivity measured by the hyperinsulinemic-euglycemic clamp. Th...

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Hlavní autoři: Xie, Weijia, Wood, Andrew R., Lyssenko, Valeriya, Weedon, Michael N., Knowles, Joshua W., Alkayyali, Sami, Assimes, Themistocles L., Quertermous, Thomas, Abbasi, Fahim, Paananen, Jussi, Häring, Hans, Hansen, Torben, Pedersen, Oluf, Smith, Ulf, Laakso, Markku, Dekker, Jacqueline M., Nolan, John J., Groop, Leif, Ferrannini, Ele, Adam, Klaus-Peter, Gall, Walter E., Frayling, Timothy M., Walker, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661655/
https://ncbi.nlm.nih.gov/pubmed/23378610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0876
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