Reevaluation of Fatty Acid Receptor 1 as a Drug Target for the Stimulation of Insulin Secretion in Humans

The role of free fatty acid receptor 1 (FFAR1/GPR40) in glucose homeostasis is still incompletely understood. Small receptor agonists stimulating insulin secretion are undergoing investigation for the treatment of type 2 diabetes. Surprisingly, genome-wide association studies did not discover diabet...

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Autors principals: Wagner, Robert, Kaiser, Gabriele, Gerst, Felicia, Christiansen, Elisabeth, Due-Hansen, Maria E., Grundmann, Manuel, Machicao, Fausto, Peter, Andreas, Kostenis, Evi, Ulven, Trond, Fritsche, Andreas, Häring, Hans-Ulrich, Ullrich, Susanne
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661642/
https://ncbi.nlm.nih.gov/pubmed/23378609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1249
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