Humoral Responses to Islet Antigen-2 and Zinc Transporter 8 Are Attenuated in Patients Carrying HLA-A*24 Alleles at the Onset of Type 1 Diabetes

The HLA-A*24 allele has shown negative associations with autoantibodies to islet antigen-2 (IA-2) and zinc transporter 8 (ZnT8) in patients with established type 1 diabetes. Understanding how this HLA class I allele affects humoral islet autoimmunity gives new insights into disease pathogenesis. We...

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Hlavní autoři: Long, Anna E., Gillespie, Kathleen M., Aitken, Rachel J., Goode, Julia C., Bingley, Polly J., Williams, Alistair J.K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661608/
https://ncbi.nlm.nih.gov/pubmed/23396399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1468
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