Early-Onset, Coexisting Autoimmunity and Decreased HLA-Mediated Susceptibility Are the Characteristics of Diabetes in Down Syndrome

OBJECTIVE: Down syndrome (DS) is associated with an increased risk of diabetes, particularly in young children. HLA-mediated risk is however decreased in children with DS and diabetes (DSD). We hypothesized that early-onset diabetes in children with DS is etiologically different from autoimmune diab...

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Main Authors:	Aitken, Rachel J., Mehers, Kay L., Williams, Alistair J., Brown, Jamie, Bingley, Polly J., Holl, Reinhard W., Rohrer, Tilman R., Schober, Edith, Abdul-Rasoul, Majedah M., Shield, Julian P.H., Gillespie, Kathleen M.
Format:	Artigo
Language:	Inglês
Published:	American Diabetes Association 2013
Subjects:	Original Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3631858/ https://ncbi.nlm.nih.gov/pubmed/23275362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-1712
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Early-Onset, Coexisting Autoimmunity and Decreased HLA-Mediated Susceptibility Are the Characteristics of Diabetes in Down Syndrome

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