The microtubule stabilizer patupilone counteracts ionizing radiation-induced matrix metalloproteinase activity and tumor cell invasion

BACKGROUND: Ionizing radiation (IR) in combination with microtubule stabilizing agents (MSA) is a promising combined treatment modality. Supra-additive treatment responses might result from direct tumor cell killing and cooperative indirect, tumor cell-mediated effects on the tumor microenvironment....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Furmanova-Hollenstein, Polina, Broggini-Tenzer, Angela, Eggel, Matthias, Millard, Anne-Laure, Pruschy, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661365/
https://ncbi.nlm.nih.gov/pubmed/23631818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-8-105
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