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The microtubule stabilizer patupilone (epothilone B) is a potent radiosensitizer in medulloblastoma cells
Concurrent radiochemotherapy for medulloblastoma includes the microtubule disrupting agent vincristine; however, vincristine alone or as part of a combined treatment regimen is highly toxic. A major goal is therefore to replace vincristine with novel potent chemotherapeutic agents—in particular, wit...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158010/ https://ncbi.nlm.nih.gov/pubmed/21743064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor069 |
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