Iloprost improves endothelial barrier function in LPS-induced lung injury

RATIONALE: Protective effects of prostacyclin and its stable analog Iloprost are mediated by elevation of intracellular cAMP leading to enhancement of peripheral actin cytoskeleton and cell-cell adhesive structures. This study tested hypothesis that iloprost may exhibit protective effects against lu...

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Bibliografiske detaljer
Main Authors: Birukova, Anna A., Wu, Tinghuai, Tian, Yufeng, Meliton, Angelo, Sarich, Nicolene, Tian, Xinyong, Leff, Alan, Birukov, Konstantin G.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661223/
https://ncbi.nlm.nih.gov/pubmed/22790920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00148311
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