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Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1
Protective effects of prostacyclin (PC) or its stable analog beraprost against agonist-induced lung vascular inflammation have been associated with elevation of intracellular cAMP and Rac GTPase signaling which inhibited the RhoA GTPase-dependent pathway of endothelial barrier dysfunction. This stud...
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| Опубликовано в: : | Biochim Biophys Acta |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372486/ https://ncbi.nlm.nih.gov/pubmed/25545047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.12.016 |
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