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Fas Ligand-Fas Signaling Participates in Light-Induced Apoptotic Death in Photoreceptor Cells

PURPOSE. We investigated the function of Fas in photoreceptors. METHODS. Postmortem human eyes and mouse-derived photoreceptor cells (661W) were examined for Fas expression by in situ hybridization and immunofluorescence. 661W cells were treated with FasL or Fas agonistic antibody, or exposed to lig...

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Autori principali: Chang, Qing, Peter, Marcus E., Grassi, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660862/
https://ncbi.nlm.nih.gov/pubmed/22499988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8928
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