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Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways

Murine L929 fibrosarcoma cells were transfected with the human Fas (APO-1/CD95) receptor, and the role of various caspases in Fas-mediated cell death was assessed. Proteolytic activation of procaspase-3 and -7 was shown by Western analysis. Acetyl-Tyr-Val-Ala-Asp-chloromethylketone and benzyloxycarb...

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Detalhes bibliográficos
Main Authors: Vercammen, Dominique, Brouckaert, Greet, Denecker, Geertrui, Van de Craen, Marc, Declercq, Wim, Fiers, Walter, Vandenabeele, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213397/
https://ncbi.nlm.nih.gov/pubmed/9730893
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