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Differential Roles of PML Isoforms
The tumor suppressor promyelocytic leukemia (PML) protein is fused to the retinoic acid receptor alpha in patients suffering from acute promyelocytic leukemia (APL). Treatment of APL patients with arsenic trioxide (As(2)O(3)) reverses the disease phenotype by a process involving the degradation of t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3660695/ https://ncbi.nlm.nih.gov/pubmed/23734343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00125 |
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