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Improvements to Robotics-Inspired Conformational Sampling in Rosetta

To accurately predict protein conformations in atomic detail, a computational method must be capable of sampling models sufficiently close to the native structure. All-atom sampling is difficult because of the vast number of possible conformations and extremely rugged energy landscapes. Here, we tes...

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Bibliografiske detaljer
Main Authors: Stein, Amelie, Kortemme, Tanja
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660577/
https://ncbi.nlm.nih.gov/pubmed/23704889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063090
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