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Improved chemical shift prediction by Rosetta conformational sampling

Chemical shift frequencies represent a time-average of all the conformational states populated by a protein. Thus, chemical shift prediction programs based on sequence and database analysis yield higher accuracy for rigid rather than flexible protein segments. Here we show that the prediction accura...

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Bibliografiska uppgifter
Huvudupphovsmän: Tian, Ye, Opella, Stanley J., Marassi, Francesca M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484222/
https://ncbi.nlm.nih.gov/pubmed/23007199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-012-9677-7
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