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Interaction between IGF-IR and ER Induced by E2 and IGF-I

Estrogen receptor (ER) is a nuclear receptor and the insulin-like growth factor-I (IGF-I) receptor (IGF-IR) is a transmembrane tyrosine kinase receptor. Estrogen and IGF-I are known to have synergistic effects on the growth of breast cancer cells. Recently, non-nuclear effects of ER have been under...

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Bibliografiske detaljer
Main Authors: Yu, Zhenghong, Gao, Weimin, Jiang, Enze, Lu, Fang, Zhang, Luo, Shi, Zhaorong, Wang, Xinxing, Chen, Longbang, Lv, Tangfeng
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660452/
https://ncbi.nlm.nih.gov/pubmed/23704881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062642
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