TGF-β Signaling Is Often Attenuated during Hepatotumorigenesis, but Is Retained for the Malignancy of Hepatocellular Carcinoma Cells

The role of transforming growth factor-beta (TGF-β) signaling in hepatocarcinogenesis remains controversial. We aimed to reveal TGF-β signaling status in human and murine tissues of hepatocellular carcinoma (HCC) and the mechanisms that mediate TGF-β’s role in regulating HCC malignancy. Here, TGF-β...

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Main Authors: Mu, Xiaoxin, Lin, Shu, Yang, Junhua, Chen, Chen, Chen, Yun, Herzig, Maryanne C., Washburn, Kenneth, Halff, Glenn A., Walter, Christi A., Sun, Beicheng, Sun, Lu-Zhe
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660330/
https://ncbi.nlm.nih.gov/pubmed/23704908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063436
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