Functional Impairment of Human Resident Cardiac Stem Cells by the Cardiotoxic Antineoplastic Agent Trastuzumab

Trastuzumab (TZM), a monoclonal antibody against the ERBB2 protein, increases survival in ERBB2-positive breast cancer patients. Its clinical use, however, is limited by cardiotoxicity. We sought to evaluate whether TZM cardiotoxicity involves inhibition of human adult cardiac-derived stem cells, in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Barth, Andreas S., Zhang, Yiqiang, Li, Taosheng, Smith, Rachel R., Chimenti, Isotta, Terrovitis, Ioannis, Davis, Darryl R., Kizana, Eddy, Ho, Alice S., O'Rourke, Brian, Wolff, Antonio C., Gerstenblith, Gary, Marbán, Eduardo
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2012
Fag:
Original Articles and Reviews
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659699/
https://ncbi.nlm.nih.gov/pubmed/23197808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2011-0016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker