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Relating protein adduction to gene expression changes: a systems approach

Modification of proteins by reactive electrophiles such as the 4-hydroxy-2-nonenal (HNE) plays a critical role in oxidant-associated human diseases. However, little is known about protein adduction and the mechanism by which protein damage elicits adaptive effects and toxicity. We developed a system...

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Detalhes bibliográficos
Main Authors: Zhang, Bing, Shi, Zhiao, Duncan, Dexter T, Prodduturi, Naresh, Marnett, Lawrence J, Liebler, Daniel C
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659419/
https://ncbi.nlm.nih.gov/pubmed/21594272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1mb05014a
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