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Relating protein adduction to gene expression changes: a systems approach
Modification of proteins by reactive electrophiles such as the 4-hydroxy-2-nonenal (HNE) plays a critical role in oxidant-associated human diseases. However, little is known about protein adduction and the mechanism by which protein damage elicits adaptive effects and toxicity. We developed a system...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3659419/ https://ncbi.nlm.nih.gov/pubmed/21594272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1mb05014a |
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