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Protein-Selective Capture to Analyze Electrophile Adduction of Hsp90 by 4-Hydroxynonenal

[Image: see text] The analysis of protein modification by electrophiles is a challenging problem. Most reported protein–electrophile adducts have been characterized from in vitro reactions or through affinity capture of the adduct moiety, which enables global analyses but is poorly suited to targete...

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Autori principali: Connor, Rebecca E., Marnett, Lawrence J., Liebler, Daniel C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2011
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155980/
https://ncbi.nlm.nih.gov/pubmed/21749116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200157t
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