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Analysis of Protein Adduction Kinetics by Quantitative Mass Spectrometry. Competing Adduction Reactions of Glutathione-S-Transferase P1-1 with Electrophiles

Defining the mechanisms and consequences of protein adduction is crucial to understanding the toxicity of reactive electrophiles. Application of tandem mass spectrometry and data analysis algorithms enables detection and mapping of chemical adducts at the level of amino acid sequence. Nevertheless,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Orton, Christopher R., Liebler, Daniel C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063493/
https://ncbi.nlm.nih.gov/pubmed/17433278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2007.03.005
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