Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

The evolutionarily conserved target of rapamycin (TOR) signaling controls growth, metabolism and aging. In the first robust demonstration of pharmacologically-induced life extension in a mammal, longevity was extended in mice treated with rapamycin, an inhibitor of mechanistic TOR (mTOR). However, d...

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Bibliografski detalji
Glavni autori: Fang, Yimin, Westbrook, Reyhan, Hill, Cristal, Boparai, Ravneet, Arum, Oge, Spong, Adam, Wang, Feiya, Javors, Martin A., Chen, Jie, Sun, Liou Y., Bartke, Andrzej
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658445/
https://ncbi.nlm.nih.gov/pubmed/23473038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.02.008
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