Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

The evolutionarily conserved target of rapamycin (TOR) signaling controls growth, metabolism and aging. In the first robust demonstration of pharmacologically-induced life extension in a mammal, longevity was extended in mice treated with rapamycin, an inhibitor of mechanistic TOR (mTOR). However, d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fang, Yimin, Westbrook, Reyhan, Hill, Cristal, Boparai, Ravneet, Arum, Oge, Spong, Adam, Wang, Feiya, Javors, Martin A., Chen, Jie, Sun, Liou Y., Bartke, Andrzej
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658445/
https://ncbi.nlm.nih.gov/pubmed/23473038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.02.008
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