Duration of Rapamycin Treatment Has Differential Effects on Metabolism in Mice

The evolutionarily conserved target of rapamycin (TOR) signaling controls growth, metabolism and aging. In the first robust demonstration of pharmacologically-induced life extension in a mammal, longevity was extended in mice treated with rapamycin, an inhibitor of mechanistic TOR (mTOR). However, d...

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Detalhes bibliográficos
Main Authors: Fang, Yimin, Westbrook, Reyhan, Hill, Cristal, Boparai, Ravneet, Arum, Oge, Spong, Adam, Wang, Feiya, Javors, Martin A., Chen, Jie, Sun, Liou Y., Bartke, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658445/
https://ncbi.nlm.nih.gov/pubmed/23473038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.02.008
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