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Dynamics of internal pore opening in K(V) channels probed by a fluorescent unnatural amino acid

Atomic-scale models on the gating mechanism of voltage-gated potassium channels (Kv) are based on linear interpolations between static structures of their initial and final state derived from crystallography and molecular dynamics simulations, and, thus, lack dynamic structural information. The lack...

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Détails bibliographiques
Auteurs principaux: Kalstrup, Tanja, Blunck, Rikard
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657800/
https://ncbi.nlm.nih.gov/pubmed/23630265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220398110
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