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Plasma membrane localization signals in the light chain of botulinum neurotoxin
Botulinum neurotoxin (BoNT) is a potent biological substance used to treat neuromuscular and pain disorders. Both BoNT type A and BoNT type E display high-affinity uptake into motor neurons and inhibit exocytosis through cleavage of the synaptosome-associated protein of 25 kDa (SNAP25). The therapeu...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365768/ https://ncbi.nlm.nih.gov/pubmed/14982988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400229101 |
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