Cardiac-specific mindin overexpression attenuates cardiac hypertrophy via blocking AKT/GSK3β and TGF-β1–Smad signalling

AIMS: Mindin is a secreted extracellular matrix protein, an integrin ligand, and an angiogenesis inhibitor, other examples of which are all key players in the progression of cardiac hypertrophy. However, its function during cardiac hypertrophy remains unclear. This study was aimed to identify the ef...

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書誌詳細
主要な著者: Yan, Ling, Wei, Xiang, Tang, Qi-Zhu, Feng, Jinghua, Zhang, Yan, Liu, Chen, Bian, Zhou-Yan, Zhang, Lian-Feng, Chen, Manyin, Bai, Xue, Wang, Ai-Bing, Fassett, John, Chen, Yingjie, He, You-Wen, Yang, Qinglin, Liu, Peter P., Li, Hongliang
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
主題:
Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657538/
https://ncbi.nlm.nih.gov/pubmed/21632881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr159
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