Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming

TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC and 5caC are excised by mammalian DNA glycosylase TDG, implicating 5mC oxidation in DNA demethylation. Here we show that the genomic locations of 5fC can be deter...

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Detalhes bibliográficos
Main Authors: Song, Chun-Xiao, Szulwach, Keith E., Dai, Qing, Fu, Ye, Mao, Shi-Qing, Lin, Li, Street, Craig, Li, Yujing, Poidevin, Mickael, Wu, Hao, Gao, Juan, Liu, Peng, Li, Lin, Xu, Guo-Liang, Jin, Peng, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657391/
https://ncbi.nlm.nih.gov/pubmed/23602153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.04.001
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